Richard R Neubig Selected Research

RGS Proteins

6/2015	Selectivity and anti-Parkinson's potential of thiadiazolidinone RGS4 inhibitors.
6/2010	RGS inhibition at G(alpha)i2 selectively potentiates 5-HT1A-mediated antidepressant effects.
1/2008	Resistance to diet-induced obesity and improved insulin sensitivity in mice with a regulator of G protein signaling-insensitive G184S Gnai2 allele.
5/2007	Endogenous RGS proteins modulate SA and AV nodal functions in isolated heart: implications for sick sinus syndrome and AV block.
2/2005	Regulators of G protein signaling & drugs of abuse.
7/2004	Endogenous regulator of G protein signaling proteins suppress Galphao-dependent, mu-opioid agonist-mediated adenylyl cyclase supersensitization.
3/2002	Regulators of G-protein signalling as new central nervous system drug targets.

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Richard R Neubig Research Topics

Disease

12	Fibrosis (Cirrhosis) 04/2019 - 05/2012
8	Melanoma (Melanoma, Malignant) 01/2022 - 08/2007
6	Neoplasms (Cancer) 01/2022 - 07/2004
6	Neoplasm Metastasis (Metastasis) 04/2019 - 08/2007
5	Movement Disorders (Movement Disorder) 01/2022 - 06/2015
5	Hypertension (High Blood Pressure) 12/2019 - 04/2007
5	Prostatic Neoplasms (Prostate Cancer) 05/2016 - 07/2004
4	Leukemia 11/2009 - 07/2004
3	Dyskinesias (Dyskinesia) 11/2021 - 11/2015
3	Obesity 01/2019 - 01/2008
3	Heart Failure 05/2016 - 05/2012
2	Cicatrix (Scar) 11/2018 - 01/2017
2	Glaucoma 11/2018 - 01/2017
2	Hyperalgesia 01/2018 - 01/2017
2	Brain Diseases (Brain Disorder) 08/2017 - 06/2014
2	Seizures (Absence Seizure) 08/2017 - 06/2014
2	Systemic Scleroderma (Systemic Sclerosis) 01/2017 - 06/2014
2	Parkinson Disease (Parkinson's Disease) 11/2015 - 06/2015
2	Bradycardia 06/2015 - 05/2007
2	Epilepsy (Aura) 06/2015 - 06/2014
2	Body Weight (Weight, Body) 05/2012 - 01/2008
2	Glioma (Gliomas) 07/2004 - 01/2004
1	COVID-19 01/2021
1	Vascular Remodeling 01/2021
1	Blister (Bulla) 11/2018
1	Eczema 01/2017
1	Ischemia 01/2017
1	Atopic Dermatitis (Atopic Eczema) 01/2017
1	Acute Megakaryoblastic Leukemia (Leukemia, Megakaryocytic) 05/2016
1	Breast Neoplasms (Breast Cancer) 05/2016
1	Cardiovascular Diseases (Cardiovascular Disease) 05/2016
1	Hypokinesia (Bradykinesia) 06/2015
1	Idiopathic Pulmonary Fibrosis 04/2015
1	Reperfusion Injury 01/2015
1	Shock 10/2012

Drug/Important Bio-Agent (IBA)

8	GTP-Binding Proteins (G-Protein)IBA 11/2021 - 08/2003
7	Proteins (Proteins, Gene)FDA Link 01/2022 - 06/2005
7	Transcription Factors (Transcription Factor)IBA 04/2021 - 06/2014
7	Serum Response FactorIBA 01/2019 - 08/2007
7	RGS ProteinsIBA 06/2015 - 03/2002
6	myocardinIBA 04/2021 - 06/2014
6	CCG 1423IBA 04/2019 - 08/2007
4	Pharmaceutical PreparationsIBA 12/2019 - 07/2014
4	Bleomycin (Blenoxane)FDA LinkGeneric 04/2019 - 04/2015
4	N- (4- chlorophenyl)- 1- ((3- (furan- 2- yl)phenyl)carbonyl)piperidine- 3- carboxamideIBA 06/2017 - 04/2015
3	Opioid Analgesics (Opioids)IBA 11/2021 - 07/2004
3	Levodopa (L Dopa)FDA LinkGeneric 11/2021 - 11/2015
2	Phosphotransferases (Kinase)IBA 01/2022 - 01/2004
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2022 - 04/2021
2	Opioid Receptors (Opioid Receptor)IBA 11/2021 - 01/2004
2	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2021 - 04/2015
2	Nitroglycerin (Dynamite)FDA LinkGeneric 01/2018 - 01/2017
2	Digoxin (Digitek)FDA LinkGeneric 05/2016 - 09/2012
2	Muscarinic M4 ReceptorIBA 01/2016 - 11/2015
2	Cholinergic Agents (Cholinergics)IBA 06/2015 - 05/2007
2	Serotonin (5 Hydroxytryptamine)IBA 01/2015 - 06/2010
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 06/2014 - 07/2004
2	matrigelIBA 07/2013 - 01/2010
2	AmidesIBA 07/2013 - 01/2010
2	CatecholaminesIBA 05/2012 - 10/2007
2	Isoproterenol (Isoprenaline)FDA LinkGeneric 05/2012 - 05/2007
2	Rho Guanine Nucleotide Exchange FactorsIBA 02/2009 - 07/2004
2	Lysophosphatidic Acid ReceptorsIBA 08/2007 - 07/2004
2	lysophosphatidic acidIBA 08/2007 - 07/2004
1	MAP Kinase Kinase 1IBA 01/2022
1	acalabrutinibIBA 01/2022
1	src-Family KinasesIBA 01/2022
1	ibrutinibIBA 01/2022
1	Cyclin B1IBA 01/2022
1	VemurafenibIBA 01/2022
1	Oxidopamine (6 Hydroxydopamine)IBA 11/2021
1	at-403IBA 11/2021
1	NociceptinIBA 11/2021
1	Cytostatic AgentsIBA 04/2021
1	trametinibIBA 04/2021
1	Risperidone (Risperdal Consta)FDA LinkGeneric 01/2020
1	LuciferasesIBA 04/2019
1	Antifibrotic AgentsIBA 01/2019
1	Codon (Codons)IBA 01/2019
1	Connective Tissue Growth FactorIBA 01/2019
1	Cyclic AMP (AMP, Cyclic)IBA 01/2018
1	DEET (DET)IBA 08/2017
1	Extracellular Matrix ProteinsIBA 06/2017
1	CytokinesIBA 06/2017
1	AdipokinesIBA 01/2017
1	Caspase 3 (Caspase-3)IBA 01/2017
1	Proteasome Endopeptidase Complex (Proteasome)IBA 05/2016
1	Adenosine Triphosphatases (ATPase)IBA 05/2016
1	RacloprideIBA 06/2015
1	piperidineIBA 04/2015
1	Plasminogen Activators (Plasminogen Activator)IBA 04/2015
1	Fibronectins (Fibronectin)IBA 04/2015
1	Antidepressive Agents (Antidepressants)IBA 01/2015
1	rho GTP-Binding Proteins (rho GTP-Binding Protein)IBA 07/2014
1	Protein Kinases (Protein Kinase)IBA 01/2014
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2012

Therapy/Procedure

10	Therapeutics 01/2022 - 06/2014
2	Filtering Surgery 11/2018 - 01/2017
1	Chemoprevention 01/2019
1	Organ Transplantation 07/2014